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Exogenous Adrenal Insufficiency


Exogenous adrenal insufficiency is a condition that results in the release of hormone cortisone by the adrenal glands. The glands release the hormone in a very little quantity. An important necessary to highlight is that despite releasing of the hormone, the glands remain in working condition i.e. there is no problem with the adrenal glands. Drug-induced adrenal insufficiency is the alternative name of the condition.

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It is believed that the disease is caused due to intake of some sort of Glucocorticoid medications. Glucocorticoid medications like hydrocortisone, prednisone, etc are used for treating variety of inflammatory conditions like asthma, few forms of arthritis, etc. When these drugs are given to people through injections or pills to treat some other maladies then the symptoms of exogenous adrenal insufficiency appear. Especially, if the higher doses of the disease are taken by a person for a long duration, chances of getting affected from the diseases increases to a great level. Additionally, if the treatment with Glucocorticoid is stooped abruptly, chances become too high from getting affected with adrenal insufficiency. Intake of some other drugs like mitotane, Ketoconazole, megestrol, etc also causes the disease.

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Signs & Symptoms

The common symptoms that are encountered by a person during the disease are:

  • Nausea and vomiting
  • Fatigue
  • Weakness
  • Low blood pressure
  • Shock
  • Joints and muscle pain
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One of the best ways of preventing the exogenous adrenal insufficiency is taking lower doses of Glucocorticoid that too for a short duration.  

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Conservative Treatment Modern Medicine

The only way of treating the disease is to give additional Glucocorticoid. Higher doses are given to the patient in severe cases.

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