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- Acromegaly
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- Cushing'S Syndrome Caused By Adrenal Tumor
- Cushing'S Syndrome; Exogenous
- Drug-Induced Hypothyroidism
- Ectopic Cushing'S Syndrome
- Empty-Sella Syndrome
- Exogenous Adrenal Insufficiency
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Cushing'S Syndrome Caused By Adrenal Tumor
Overview
Causes
Constant high level of cortical; steroid hormone is main cause of this disease.15% of Cushing syndrome is caused by tumor on one of the gland. Cortisol is released in larger amount by adrenal tumor.
Adrenal tumors are divided into
1) Cancerous (malignant)
2) Non-cancerous (benign)
Adrenal tumors are rare and can occur at any age of time. This condition is more common in women than men.
80% of Cushing syndrome is ACTH Dependent
- Lung cancers (5%)
- Pituitary tumors (60%)
ACTH Independent is 20%
- Malignant adrenal tumors (adrenal cell carcinoma) (10%)
- Benign adrenal tumors (adenoma) (25%)
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Signs & Symptoms
- Upper body obesity spl in waist region with thin legs and arms.
- Moon face (round, red )
- Slow growth in children
- Common skin changes include
- skin infection
-acne
-striae ; purple color marks on abdomen, breast and thigh region
-increase in skin sensitivity as skin becomes thin and gets bruised easily - Common muscle and bone changes includes:
- muscular weakness
-backache
- thinning of bones
- buffalo hump ;collection of fat between shoulders
-bony pain and tenderness - Excess growth of hairs on face, neck,chest,abdomen and chest spl in women
- Menstrual cycle become irregular or stops
- Decrease in fertility , loss of libido are few of the symptom in men
Other symptom may include:
- Fatigue
- Mental change; depression, anxiety,behaviorial changes
- Headache
- Back pain
- Increase thirst and urine output
Prevention
Treatments
| Surgery | Modern Medicine |
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Treatment depends on the cause. Surgery is common treatment for removal of tumor followed by radiation therapy. |
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