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A chronic metabolic disorder that results in gradual enlargement of tissues including the bones of the face, jaw, hands, feet, and skull.

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Acromegaly, a condition caused by increased secretion of growth hormone after normal growth has been completed, occurs in adults. When excessive secretion of growth hormone occurs in children before normal growth has been completed, it causes gigantism rather than acromegaly. The cause of the increased hormone secretion is usually a benign pituitary tumor. The pituitary gland, which is located at the base of the brain, controls the production and release of several different hormones. There are no known risk factors other than prior history of a pituitary tumor.

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Signs & Symptoms

enlarged hands- enlarged feet- widened fingers or toes due to skin overgrowth with swelling, redness, and pain.- enlarged jaw (prognathism)- enlarged facial bones- thickening of the skin- enlarged sebaceous glands- hoarseness- headache- double vision- vomiting- easy fatigue- excessive sweating- decreased muscle strength (weakness)- motion limitation, or loss of range of motion- joint pain (hip pain, knee pain, ankle pain, foot pain, pain over the small joints of the foot, shoulder pain, elbow pain, wristpain, hand pain, pain over the small joints of the hand, or pain in any other joint)- carpal tunnel syndrome- change in face appearance, developed over less than 1 year- widely spaced teeth- swelling of the bony areas around a jointIn infants anterior fontanel can remain open for years.Additional symptoms that may be associated with this disease:- weight gain (unintentional)- tongue problems- skin, abnormally dark or light- hair, excessive on females

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No measures exist to prevent the initial condition, but early treatment may prevent any worsening of complications associated with this disease.

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Combination Therapy Modern Medicine

Treatment of acromegaly aims on stopping or to reduce the overproduction of growth hormone. Treatment includes Surgery, Radiation therapy and chemotherapy.

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